Adjudin disrupts spermatogenesis by targeting drug transporters: Lesson from the breast cancer resistance protein (BCRP)

For non-hormonal male contraceptives that exert their effects in the testis locally instead of via the hypothalamic-pituitary-testicular axis, such as adjudin that disrupts germ cell adhesion, a major hurdle in their development is to improve their bioavailability so that they can be efficiently del...

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Main Authors: Qian, Xiaojing, Cheng, Yan-ho, Jenardhanan, Pranitha, Mruk, Dolores D., Mathur, Premendu P., Xia, Weiliang, Silvestrini, Bruno, Cheng, C. Yan
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
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Views, Commentaries & Opinions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710224/
https://ncbi.nlm.nih.gov/pubmed/23885306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/spmg.24993
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