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Brain pericytes increase the lipopolysaccharide-enhanced transcytosis of HIV-1 free virus across the in vitro blood–brain barrier: evidence for cytokine-mediated pericyte-endothelial cell crosstalk

BACKGROUND: Human immunodeficiency virus-1 (HIV-1) enters the brain by crossing the blood–brain barrier (BBB) as both free virus and within infected immune cells. Previous work showed that activation of the innate immune system with lipopolysaccharide (LPS) enhances free virus transport both in vivo...

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Detalhes bibliográficos
Main Authors: Dohgu, Shinya, Banks, William A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710206/
https://ncbi.nlm.nih.gov/pubmed/23816186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-10-23
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