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Brain pericytes increase the lipopolysaccharide-enhanced transcytosis of HIV-1 free virus across the in vitro blood–brain barrier: evidence for cytokine-mediated pericyte-endothelial cell crosstalk
BACKGROUND: Human immunodeficiency virus-1 (HIV-1) enters the brain by crossing the blood–brain barrier (BBB) as both free virus and within infected immune cells. Previous work showed that activation of the innate immune system with lipopolysaccharide (LPS) enhances free virus transport both in vivo...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710206/ https://ncbi.nlm.nih.gov/pubmed/23816186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-10-23 |
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