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Brain pericytes increase the lipopolysaccharide-enhanced transcytosis of HIV-1 free virus across the in vitro blood–brain barrier: evidence for cytokine-mediated pericyte-endothelial cell crosstalk

BACKGROUND: Human immunodeficiency virus-1 (HIV-1) enters the brain by crossing the blood–brain barrier (BBB) as both free virus and within infected immune cells. Previous work showed that activation of the innate immune system with lipopolysaccharide (LPS) enhances free virus transport both in vivo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dohgu, Shinya, Banks, William A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710206/
https://ncbi.nlm.nih.gov/pubmed/23816186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-10-23
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