CXCL12-Induced Monocyte-Endothelial Interactions Promote Lymphocyte Transmigration Across an in Vitro Blood-Brain Barrier

The accumulation of inflammatory cells in the brain parenchyma is a critical step in the pathogenesis of neuroinflammatory diseases such as multiple sclerosis (MS). Chemokines and adhesion molecules orchestrate leukocyte transmigration across the blood-brain barrier (BBB), but the dynamics of chemok...

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Bibliographic Details
Main Authors: Man, Shumei, Tucky, Barbara, Cotleur, Anne, Drazba, Judith, Takeshita, Yukio, Ransohoff, Richard M.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710123/
https://ncbi.nlm.nih.gov/pubmed/22301555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003197
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