Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing

BACKGROUND: The major role of enzymatic toxins that target nucleic acids in biological conflicts at all levels has become increasingly apparent thanks in large part to the advances of comparative genomics. Typically, toxins evolve rapidly hampering the identification of these proteins by sequence an...

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Main Authors: Anantharaman, Vivek, Makarova, Kira S, Burroughs, A Maxwell, Koonin, Eugene V, Aravind, L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710099/
https://ncbi.nlm.nih.gov/pubmed/23768067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-8-15
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