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Significance of Cross-Linking of α(2)-Plasmin Inhibitor to Fibrin in Inhibition of Fibrinolysis and in Hemostasis

When blood is clotted, α(2)-plasmin inhibitor (α(2)PI) is cross-linked to fibrin by activated fibrin-stabilizing factor (activated coagulation Factor XIII, plasma transglutaminase). The amount of cross-linked α(2)-PI is proportional to the amount of α(2)PI present at the time of clotting. Plasma fro...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Sakata, Yoichi, Aoki, Nobuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1982
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7199538/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110479
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