Increased enzymatic activity of the alternative pathway convertase when bound to the erythrocytes of paroxysmal nocturnal hemoglobinuria.

To investigate the greater fixation of C3 to the erythrocytes of patients with paroxysmal nocturnal hemoglobinuria (PNH) upon activation of complement, we have examined the formation and the reaction of the C3 nephritic factor-stabilized alternative pathway convertase made with purified components o...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Parker, C J, Baker, P J, Rosse, W F
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1982
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6915939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110457
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