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Tracking the Interplay between Bound Peptide and the Lid Domain of DnaK, Using Molecular Dynamics
Hsp70 chaperones consist of two functional domains: the 44 kDa Nucleotide Binding Domain (NBD), that binds and hydrolyses ATP, and the 26 kDa Substrate Binding Domain (SBD), which binds unfolded proteins and reactivates them, utilizing energy obtained from nucleotide hydrolysis. The structure of the...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Molecular Diversity Preservation International (MDPI)
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3709807/ https://ncbi.nlm.nih.gov/pubmed/23774839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140612675 |
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