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Tracking the Interplay between Bound Peptide and the Lid Domain of DnaK, Using Molecular Dynamics

Hsp70 chaperones consist of two functional domains: the 44 kDa Nucleotide Binding Domain (NBD), that binds and hydrolyses ATP, and the 26 kDa Substrate Binding Domain (SBD), which binds unfolded proteins and reactivates them, utilizing energy obtained from nucleotide hydrolysis. The structure of the...

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Detalhes bibliográficos
Main Authors: Azoulay, Itzhaq, Kucherenko, Nataly, Nachliel, Esther, Gutman, Menachem, Azem, Abdussalam, Tsfadia, Yossi
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709807/
https://ncbi.nlm.nih.gov/pubmed/23774839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140612675
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