Knockdown of piRNA pathway proteins results in enhanced Semliki Forest virus production in mosquito cells

The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described following infection of mosquitoes and derived...

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Autores principales: Schnettler, Esther, Donald, Claire L., Human, Stacey, Watson, Mick, Siu, Ricky W. C., McFarlane, Melanie, Fazakerley, John K., Kohl, Alain, Fragkoudis, Rennos
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for General Microbiology 2013
Materias:
Insect
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709635/
https://ncbi.nlm.nih.gov/pubmed/23559478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.053850-0
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