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Inhibition of indoleamine 2,3-dioxygenase enhances the T-cell response to influenza virus infection
Influenza infection induces an increase in the level of indoleamine 2,3-dioxygenase (IDO) activity in the lung parenchyma. IDO is the first and rate-limiting step in the kynurenine pathway where tryptophan is reduced to kynurenine and other metabolites. The depletion of tryptophan, and production of...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for General Microbiology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3709631/ https://ncbi.nlm.nih.gov/pubmed/23580425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.053124-0 |
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