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Creation of a completely helper cell-dependent recombinant morbillivirus

We have created a completely helper cell-dependent morbillivirus by modifying the genome to remove the coding sequence of the phosphoprotein (P) and recovering the recombinant virus in a cell line constitutively expressing the P protein. The P protein-deleted virus (P(−)) grew very inefficiently unl...

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Detalhes bibliográficos
Main Authors: Baron, Jana, Baron, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709626/
https://ncbi.nlm.nih.gov/pubmed/23426357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.050872-0
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