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Liver X receptor α activation with the synthetic ligand T0901317 reduces lung injury and inflammation after hemorrhage and resuscitation via inhibition of the NF-κB pathway
Liver X Receptor α is a nuclear transcription factor that regulates lipid metabolism. Recently, it has been shown that activation of LXRα with synthetic ligands has anti-inflammatory effects in atherosclerosis and chemical-induced dermatitis. Here, we investigated the effect of the LXRα agonist T090...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3709435/ https://ncbi.nlm.nih.gov/pubmed/20926989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181f7d742 |
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