Characterization of the defect in activation of factor IX Chapel Hill by human factor XIa.

Factor IXChapel Hill (Factor IXCH), an abnormal Factor IX molecule isolated from the plasma of a patient with mild hemophilia B, has previously been shown to exhibit delayed activation by Factor XIa and calcium. In this study, we have found that Factor IXCH is cleaved upon incubation with human Fact...

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Pubblicato in:	J Clin Invest
Autori principali:	Braunstein, K M, Noyes, C M, Griffith, M J, Lundblad, R L, Roberts, H R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370943/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6976355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110393
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