Bone marrow transplantation only partially restores purine metabolites to normal in adenosine deaminase-deficient patients.

To delineate the extent to which bone marrow transplantation provides "enzyme replacement therapy", we have determined metabolite concentrations in two patients with adenosine deaminase (ADA) deficiency treated with bone marrow transplants and rendered immunologically normal. 10 yr after engraftment...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Clin Invest
Autori principali:	Hirschhorn, R, Roegner-Maniscalco, V, Kuritsky, L, Rosen, F S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7033281/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110389
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!