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Analysis of Cellular Localization and Function of Carboxy-Terminal Mutants of Pendrin

BACKGROUND: Iodide uptake at the basolateral membrane and iodide efflux at the apical membrane of thyrocytes, essential steps in the biosynthesis of thyroid hormone, are stimulated by thyroid stimulating hormone (TSH). Pendrin (SLC26A4) is inserted into the apical membrane of thyrocytes and thought...

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Autores principales: Bizhanova, Aigerim, Chew, Teng-Leong, Khuon, Satya, Kopp, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709185/
https://ncbi.nlm.nih.gov/pubmed/22116356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000335105
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