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Collagen and Collagen-derived Fragments Are Chemotactic for Tumor Cells

Organs that are rich in collagen such as liver, lungs, and bone are frequently sites of tumor cell metastasis. In this study, we have found that cultured tumor cells of human and rat origin migrated unidirectionally in response to collagen in vitro. Synthetic di- and tri-peptides that contained amin...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Mundy, Gregory R., Demartino, Sandra, Rowe, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1981
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370899/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7287902/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110334
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