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Inhibition of PbGP43 Expression May Suggest that gp43 is a Virulence Factor in Paracoccidioides brasiliensis

Glycoprotein gp43 is an immunodominant diagnostic antigen for paracoccidioidomycosis caused by Paracoccidioides brasiliensis. It is abundantly secreted in isolates such as Pb339. It is structurally related to beta-1,3-exoglucanases, however inactive. Its function in fungal biology is unknown, but it...

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Bibliographische Detailangaben
Hauptverfasser: Torres, Isaura, Hernandez, Orville, Tamayo, Diana, Muñoz, Jose F., Leitão, Natanael P., García, Ana M., Restrepo, Angela, Puccia, Rosana, McEwen, Juan G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708949/
https://ncbi.nlm.nih.gov/pubmed/23874627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068434
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