A Single Immunization with MVA Expressing GnGc Glycoproteins Promotes Epitope-specific CD8+-T Cell Activation and Protects Immune-competent Mice against a Lethal RVFV Infection

BACKGROUND: Rift Valley fever virus (RVFV) is a mosquito-borne pathogen causing an important disease in ruminants often transmitted to humans after epizootic outbreaks in African and Arabian countries. To help combat the spread of the disease, prophylactic measures need to be developed and/or improv...

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Detalhes bibliográficos
Main Authors: López-Gil, Elena, Lorenzo, Gema, Hevia, Esther, Borrego, Belén, Eiden, Martin, Groschup, Martin, Gilbert, Sarah C., Brun, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708870/
https://ncbi.nlm.nih.gov/pubmed/23875044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002309
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