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Protein kinase C-δ isoform mediates lysosome labilization in DNA damage-induced apoptosis
A lysosomal pathway, characterized by the partial rupture or labilization of lysosomal membranes (LLM) and cathepsin release into the cytosol, is evoked during the early events of 20-S-camptothecin lactone (CPT)-induced apoptosis in human cancer cells, including human histiocytic lymphoma U-937 cell...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708863/ https://ncbi.nlm.nih.gov/pubmed/21174057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2010.881 |
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