Hierarchical Modeling for Rare Event Detection and Cell Subset Alignment across Flow Cytometry Samples

Flow cytometry is the prototypical assay for multi-parameter single cell analysis, and is essential in vaccine and biomarker research for the enumeration of antigen-specific lymphocytes that are often found in extremely low frequencies (0.1% or less). Standard analysis of flow cytometry data relies...

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Autori principali: Cron, Andrew, Gouttefangeas, Cécile, Frelinger, Jacob, Lin, Lin, Singh, Satwinder K., Britten, Cedrik M., Welters, Marij J. P., van der Burg, Sjoerd H., West, Mike, Chan, Cliburn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708855/
https://ncbi.nlm.nih.gov/pubmed/23874174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003130
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