NF-κB activation in myeloid cells mediates ventilator-induced lung injury

BACKGROUND: Although use of the mechanical ventilator is a life-saving intervention, excessive tidal volumes will activate NF-κB in the lung with subsequent induction of lung edema formation, neutrophil infiltration and proinflammatory cytokine/chemokine release. The roles of NF-κB and IL-6 in venti...

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Detalhes bibliográficos
Main Authors: Ko, Yi-An, Yang, Ming-Chieh, Huang, Hung-Tu, Hsu, Ching-Mei, Chen, Lee-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708752/
https://ncbi.nlm.nih.gov/pubmed/23822633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-69
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