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Role of Cells in Freezing-Induced Cell-Fluid-Matrix Interactions Within Engineered Tissues

During cryopreservation, ice forms in the extracellular space resulting in freezing-induced deformation of the tissue, which can be detrimental to the extracellular matrix (ECM) microstructure. Meanwhile, cells dehydrate through an osmotically driven process as the intracellular water is transported...

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Detalhes bibliográficos
Main Authors: Seawright, Angela, Ozcelikkale, Altug, Dutton, Craig, Han, Bumsoo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Mechanical Engineers 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708713/
https://ncbi.nlm.nih.gov/pubmed/23719856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4024571
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