Tumour morphology predicts PALB2 germline mutation status

BACKGROUND: Population-based studies of breast cancer have estimated that at least some PALB2 mutations are associated with high breast cancer risk. For women carrying PALB2 mutations, knowing their carrier status could be useful in directing them towards effective cancer risk management and therape...

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Autors principals: Teo, Z L, Provenzano, E, Dite, G S, Park, D J, Apicella, C, Sawyer, S D, James, P A, Mitchell, G, Trainer, A H, Lindeman, G J, Shackleton, K, Cicciarelli, L, Buys, S S, Andrulis, I L, Mulligan, A M, Glendon, G, John, E M, Terry, M B, Daly, M, Odefrey, F A, Nguyen-Dumont, T, Giles, G G, Dowty, J G, Winship, I, Goldgar, D E, Hopper, J L, Southey, M C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708559/
https://ncbi.nlm.nih.gov/pubmed/23787919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.295
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