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The Effect of Gene Overlapping on the Rate of RNA Virus Evolution

Gene overlapping is widely employed by RNA viruses to generate genetic novelty while retaining a small genome size. However, gene overlapping also increases the deleterious effect of mutations as they affect more than one gene, thereby reducing the evolutionary rate of RNA viruses and hence their ad...

詳細記述

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書誌詳細
主要な著者: Simon-Loriere, Etienne, Holmes, Edward C., Pagán, Israel
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708502/
https://ncbi.nlm.nih.gov/pubmed/23686658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst094
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