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Analysis of piRNA-Mediated Silencing of Active TEs in Drosophila melanogaster Suggests Limits on the Evolution of Host Genome Defense
The Piwi-interacting RNA (piRNA) pathway defends animal genomes against the harmful consequences of transposable element (TE) infection by imposing small-RNA-mediated silencing. Because silencing is targeted by TE-derived piRNAs, piRNA production is posited to be central to the evolution of genome d...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708497/ https://ncbi.nlm.nih.gov/pubmed/23625890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst081 |
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