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Analysis of piRNA-Mediated Silencing of Active TEs in Drosophila melanogaster Suggests Limits on the Evolution of Host Genome Defense

The Piwi-interacting RNA (piRNA) pathway defends animal genomes against the harmful consequences of transposable element (TE) infection by imposing small-RNA-mediated silencing. Because silencing is targeted by TE-derived piRNAs, piRNA production is posited to be central to the evolution of genome d...

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Detalles Bibliográficos
Main Authors: Kelleher, Erin S., Barbash, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708497/
https://ncbi.nlm.nih.gov/pubmed/23625890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst081
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