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DICER1 Mutations in Embryonal Rhabdomyosarcomas from Children With and Without Familial PPB-Tumor Predisposition Syndrome

Embryonal rhabdomyosarcoma (ERMS) is the most common sarcoma of childhood and is a component of the familial Pleuropulmonary Blastoma (PPB)-predisposition syndrome. Using the PPB model, we hypothesized that DICER1 mutations would be found in familial and sporadic forms of ERMS. Blood samples from fo...

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Autors principals: Doros, Leslie, Yang, Jiandong, Dehner, Louis, Rossi, Christopher T., Skiver, Kerry, Jarzembowski, Jason, Messinger, Yoav, Schultz, Kris Ann, Williams, Gretchen, Hill, D. Ashley
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708486/
https://ncbi.nlm.nih.gov/pubmed/22180160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24020
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