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Three-dimensional reconstruction of protein networks provides insight into human genetic disease
In an effort to understand molecular mechanisms of human disease and to determine genes responsible, we systematically examine relationships between 3,949 genes, 62,663 mutations and 3,453 associated disorders within the framework of a three-dimensional structurally resolved human interactome, consi...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708476/ https://ncbi.nlm.nih.gov/pubmed/22252508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2106 |
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