Hepatoprotective and Antioxidant Effects of Saponarin, Isolated from Gypsophila trichotoma Wend. on Paracetamol-Induced Liver Damage in Rats

The hepatoprotective potential of saponarin, isolated from Gypsophila trichotoma, was evaluated in vitro/in vivo using a hepatotoxicity model of paracetamol-induced liver injury. In freshly isolated rat hepatocytes, paracetamol (100 μmol) led to a significant decrease in cell viability, increased LD...

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Bibliographic Details
Main Authors: Simeonova, Rumyana, Vitcheva, Vessela, Kondeva-Burdina, Magdalena, Krasteva, Ilina, Manov, Vassil, Mitcheva, Mitka
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708395/
https://ncbi.nlm.nih.gov/pubmed/23878818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/757126
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