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Altered spectrin dimer-dimer association and instability of erythrocyte membrane skeletons in hereditary pyropoikilocytosis.

Hereditary pyropoikilocytosis (HPP) is a hemolytic anemia characterized by microspherocytosis, poikilocytosis, and an unusual thermal sensitivity of erythrocytes. We have investigated the contribution of abnormal membrane skeletal assembly to these abnormal HPP erythrocyte properties. Skeletons prep...

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Pubblicato in:J Clin Invest
Autori principali: Liu, S C, Palek, J, Prchal, J, Castleberry, R P
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370839/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7276161/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110293
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