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Power of Single- vs. Multi-Marker Tests of Association

Current genome-wide association studies still heavily rely on a single-marker strategy, in which each single nucleotide polymorphism (SNP) is tested individually for association with a phenotype. Although methods and software packages that consider multimarker models have become available, they have...

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Detalhes bibliográficos
Main Authors: Wang, Xuefeng, Morris, Nathan J., Schaid, Daniel J., Elston, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708310/
https://ncbi.nlm.nih.gov/pubmed/22648939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21642
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