Inhibition of human polymorphonuclear leukocyte function by 2-cyclohexene-1-one. A role for glutathione in cell activation.

2-cyclohexene-1-one and diethyl maleate specifically decrease reduced glutathione (GSH) levels in human polymorphonuclear leukocytes (PMN) by direct conjugation, and by interaction with the glutathione-s-transferase system. Using these two nontoxic reagents we have examined the effect of decreased G...

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Pubblicato in:	J Clin Invest
Autori principali:	Wedner, H J, Simchowitz, L, Stenson, W F, Fischman, C M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370828/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6267107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110285
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