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Changes in the sensitivity of GABA(A) current rundown to drug treatments in a model of temporal lobe epilepsy

The pharmacological treatment of mesial temporal lobe epilepsy (mTLE), the most common epileptic syndrome in adults, is still unsatisfactory, as one-third of the patients are or become refractory to antiepileptic agents. Refractoriness may depend upon drug-induced alterations, but the disease per se...

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Detalhes bibliográficos
Main Authors: Cifelli, Pierangelo, Palma, Eleonora, Roseti, Cristina, Verlengia, Gianluca, Simonato, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708152/
https://ncbi.nlm.nih.gov/pubmed/23874269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00108
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