1,25-dihydroxyvitamin D(3) Activates MMP13 Gene Expression in Chondrocytes through p38 MARK Pathway

Osteoarthritis (OA) is the most prevalent degenerative joint disease. The highly regulated balance of matrix synthesis and degradation is disrupted in OA, leading to progressive breakdown of articular cartilage. The molecular events and pathways involved in chondrocyte disfunction of cartilage in OA...

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Bibliographic Details
Main Authors: Chen, Dafu, Li, Yang, Dai, Xuejun, Zhou, Xinhua, Tian, Wei, Zhou, Yixin, Zou, Xuenong, Zhang, Chi
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2013
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708044/
https://ncbi.nlm.nih.gov/pubmed/23847446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.6726
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