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NMR- and Circular Dichroism-monitored Lipid Binding Studies Suggest a General Role for the FATC Domain as Membrane Anchor of Phosphatidylinositol 3-Kinase-related Kinases (PIKK)

The FATC domain is shared by all members of the family of phosphatidylinositol-3 kinase-related kinases (PIKKs). It has been shown that the FATC domain plays an important role for the regulation of each PIKK. However, other than an involvement in protein-protein interactions, a common principle for...

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Bibliografische gegevens
Hoofdauteurs: Sommer, Lisa A. M., Schaad, Martin, Dames, Sonja A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707702/
https://ncbi.nlm.nih.gov/pubmed/23671275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.467233
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