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The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential
The potent actions of pigment epithelium-derived factor (PEDF) on tumour-associated cells, and its extracellular localization and secretion, stimulated research on this multifunctional serpin. Such studies have identified several PEDF receptors and downstream signalling pathways. Known cellular PEDF...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707632/ https://ncbi.nlm.nih.gov/pubmed/23486238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3484 |
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