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Activity-dependent Transcriptional Regulation of M-type (Kv7) K(+) Channels by AKAP79/150-mediated NFAT Actions

M-type K(+) channels, encoded by the KCNQ2-5 (Kv7) gene family, play key roles in regulation of neuronal excitability; however, less is known about the mechanisms controlling their transcriptional expression. Here, we discovered a novel mechanism regulating KCNQ2/3 transcriptional expression by neur...

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Detalhes bibliográficos
Main Authors: Zhang, Jie, Shapiro, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707625/
https://ncbi.nlm.nih.gov/pubmed/23259949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.10.019
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