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Abnormal platelet response to thromboxane A2.

To determine the pathogenetic mechanism of a hereditary primary platelet release disorder, arachidonic acid metabolism via the cyclooxygenase pathway was investigated. The propositus' platelets exhibited defective release reaction and second-wave aggregation when stimulated by sodium arachidonate or...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Wu, K K, Le Breton, G C, Tai, H H, Chen, Y C
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1981
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6263954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110221
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