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Optimal Germinal Center B cell Activation and T-dependent Antibody Responses Require the Expression of the Mouse Complement Receptor Cr1

Follicular dendritic cells and complement receptors 1 and 2 are important for the generation of humoral immunity. Cr1/2 expression on B cells and FDC has been shown to provide a secondary signal for B cell activation, to facilitate transport of antigen in immune follicles, and to enhance retention o...

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Bibliografiske detaljer
Main Authors: Donius, Luke R., Handy, Jennifer M., Weis, Janis J., Weis, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707406/
https://ncbi.nlm.nih.gov/pubmed/23733878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203176
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