PGC1α-mediated Mitofusin-2 Deficiency in Female Rats and Humans with Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is a lethal, female-predominant, vascular disease. Pathologic changes in PA smooth muscle cells (PASMC) include excessive proliferation, apoptosis-resistance, and mitochondrial fragmentation. Activation of dynamin-related protein increases mitotic fis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ryan, John J., Marsboom, Glenn, Fang, Yong-Hu, Toth, Peter T., Morrow, Erik, Luo, Nancy, Piao, Lin, Hong, Zhigang, Ericson, Kyle, Zhang, Hannah J., Han, Mei, Haney, Chad R., Chen, Chin-Tu, Sharp, Willard W., Archer, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707374/
https://ncbi.nlm.nih.gov/pubmed/23449689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201209-1687OC
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados