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Targeting interleukin-17 in patients with active rheumatoid arthritis: rationale and clinical potential
Clinical and experimental evidence suggest that interleukin-17A (IL-17A; also known as IL-17) is an attractive therapeutic target in rheumatoid arthritis (RA). Rheumatoid synovial tissue produces IL-17A, which causes cartilage and bone degradation in synovial and bone explants. Overexpression of IL-...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707345/ https://ncbi.nlm.nih.gov/pubmed/23858337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X13485328 |
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