Effects of Spironolactone on Cerebral Vessel Structure in Rats With Sustained Hypertension

BACKGROUND: Spironolactone prevents eutrophic middle cerebral artery (MCA) remodeling in young stroke-prone spontaneously hypertensive rats (SHRSP). Clinically, it is more relevant to identify treatments that improve vessel structure after hypertension and remodeling has developed. We hypothesized t...

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Hlavní autoři: Rigsby, Christiné S., Ergul, Adviye, Dobos, Vera Portik, Pollock, David M., Dorrance, Anne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707290/
https://ncbi.nlm.nih.gov/pubmed/21350432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2011.20
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