Phagocytosing human neutrophils inactivate their own granular enzymes.

During phagocytosis, neutrophils generate reactive oxygen metabolites and release lysosomal enzymes into the extracellular medium. We have investigated the possibility that these enzyme are inactivated by the oxygen compounds. Phagocytosing neutrophils from 12 patients with chronic granulomatous dis...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Voetman, A A, Weening, R S, Hamers, M N, Meerhof, L J, Bot, A A, Roos, D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1981
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7229038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110185
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