Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9

Pentosan polysulfate (PPS), a heparinoid compound essentially devoid of anticoagulant activity, modulates cell growth and decreases inflammation. We investigated the effect of PPS on the progression of established atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) rabbits. After severe athe...

Full description

Saved in:
Bibliographic Details
Main Authors: Lupia, Enrico, Zheng, Feng, Grosjean, Fabrizio, Tack, Ivan, Doublier, Sophie, Elliot, Sharon J, Vlassara, Helen, Striker, Gary E
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707145/
https://ncbi.nlm.nih.gov/pubmed/22042083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.154
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items