Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9

Pentosan polysulfate (PPS), a heparinoid compound essentially devoid of anticoagulant activity, modulates cell growth and decreases inflammation. We investigated the effect of PPS on the progression of established atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) rabbits. After severe athe...

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Huvudupphovsmän: Lupia, Enrico, Zheng, Feng, Grosjean, Fabrizio, Tack, Ivan, Doublier, Sophie, Elliot, Sharon J, Vlassara, Helen, Striker, Gary E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707145/
https://ncbi.nlm.nih.gov/pubmed/22042083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.154
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