Intra-amniotic LPS amplifies hyperoxia-induced airway hyperreactivity in neonatal rats

BACKGROUND: We previously showed that intra-amniotic lipopolysaccharide (LPS) amplifies alveolar hypoplasia induced by postnatal hyperoxia. We determined whether the priming effect of intra-amniotic LPS amplifies hyperoxia-induced airway hyperreactivity (AHR). METHODS: LPS or normal saline was injec...

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Main Authors: Choi, Chang Won, Kim, Beyong Il, Mason, Stanley N., Potts-Kant, Erin N., Brahmajothi, Mulugu V., Auten, Richard L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2013
Ábhair:
Basic Science Investigation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707085/
https://ncbi.nlm.nih.gov/pubmed/23563192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2013.58
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