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Have we learnt all we need to know from genetic studies - is genetics over in Alzheimer's disease?

BACKGROUND: Alzheimer's disease (AD) pathophysiology is mostly (>95%) not inherited in a Mendelian fashion. Such sporadic AD (sAD) forms do not exhibit familial aggregation and are characterized by complex genetic inheritance. Growing evidence indicates that multiple genes contribute to sAD-...

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Detalles Bibliográficos
Main Authors: Hampel, Harald, Lista, Simone
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706946/
https://ncbi.nlm.nih.gov/pubmed/23510020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt165
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