Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneurons

INTRODUCTION: The use of immortalized neural stem cells either as models of neural development in vitro or as cellular therapies in central nervous system (CNS) disorders has been controversial. This controversy has centered on the capacity of immortalized cells to retain characteristic features of...

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Main Authors: Cocks, Graham, Romanyuk, Nataliya, Amemori, Takashi, Jendelova, Pavla, Forostyak, Oksana, Jeffries, Aaron R, Perfect, Leo, Thuret, Sandrine, Dayanithi, Govindan, Sykova, Eva, Price, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706922/
https://ncbi.nlm.nih.gov/pubmed/23759128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt220
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