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Steroid responses in sepsis: some novel thinking that may provide new insight

Glucocorticoid use in sepsis is controversial. In contrast to other extracellular signaling molecules, glucocorticoid receptors (GRs) are intra-cytoplasmic. Several GR isoforms have been identified. A study in Critical Care Forum suggests that sepsis alters the abundance of the dominant negative GRβ...

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Detalles Bibliográficos
Autor Principal: Deutschman, Clifford S
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706853/
https://ncbi.nlm.nih.gov/pubmed/23826670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc12723
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