Muscle-derived stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration

INTRODUCTION: Loss of adult stem cell function during aging contributes to impaired tissue regeneration. Here, we tested the aging-related decline in regeneration potential of adult stem cells residing in the skeletal muscle. METHODS: We isolated muscle-derived stem/progenitor cells (MDSPCs) from pr...

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Detalhes bibliográficos
Main Authors: Song, Minjung, Lavasani, Mitra, Thompson, Seth D, Lu, Aiping, Ahani, Bahar, Huard, Johnny
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706820/
https://ncbi.nlm.nih.gov/pubmed/23531345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt183
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