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Severe sepsis: are PROWESS and PROWESS-SHOCK trials comparable? A clinical and statistical heterogeneity analysis

Despite the same manufacturer, the same drotrecogin alfa activated dose, and the same placebo-controlled design, the negative result from the PROWESS-SHOCK trial contradicted the survival benefit observed in the PROWESS trial. We hypothesize that the different results were due to factors other than...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kalil, Andre C, Florescu, Diana F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706817/
https://ncbi.nlm.nih.gov/pubmed/23826709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc12752
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