Paradoxical impairment of angiogenesis, endothelial function and circulating number of endothelial progenitor cells in DPP4-deficient rat after critical limb ischemia

INTRODUCTION: We hypothesized that dipeptidyl peptidase-IV (DPP4) may impair angiogenesis, endothelial function, and the circulating number of endothelial progenitor cells (EPC) in a model of critical limb ischemia (CLI) through ligating the left femoral artery using DPP4-deficient rats. METHODS: Ad...

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Hauptverfasser: Sun, Cheuk-Kwan, Leu, Steve, Sheu, Jiunn-Jye, Tsai, Tzu-Hsien, Sung, Hsin-Chin, Chen, Yung-Lung, Chung, Sheng-Ying, Ko, Sheung-Fat, Chang, Hsueh-Wen, Yip, Hon-Kan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706813/
https://ncbi.nlm.nih.gov/pubmed/23517567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt181
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